Aramis Ramirez ended two streaks with his fifth home run Saturday night, but Rob Bowen hit a walk-off homer in the 10th inning to lift the San Diego Padres to a 2-1 victory over the Cubs.

The Cubs dropped their fifth straight and have been outscored, 22-2, in that stretch.

"If I knew the answer," Cubs manager Dusty Baker said, "we wouldn't be in this situation."

This game ended way past most Cubs fans' bedtime. With the game tied at 1 in the Padres' 10th, Bowen drove a 1-1 pitch from Bob Howry (2-1) over the right-field fence. It was the third walk-off homer by the Padres this year.

How bad was it? Jacque Jones moved into the fourth spot in the order, went 0-for-5 and struck out four times, stranding four runners.

"I can't speak for everybody else," Jones said, trying to explain the offensive woes. "I'm just trying to plug along and trying to make progress every day, and tonight I ruined it. I've been getting good at-bats, hitting the ball decent. Tonight, I was in positions to help the team win and I didn't do anything at all.

"These guys are busting their tails," Jones said. "I didn't do anything to help them."

This isn't his first skid.

"Every year, I've been in a situation where you don't score very many runs and you go through a rut and lose a few games in a row," he said. "Good teams keep plugging, and I think we have a good team. All we can do is keep fighting and keep battling. We got one run today. We've just got to start small. We got one. Let's try to build on it tomorrow."

It was a game of inches in the San Diego eighth. Eric Young singled to lead off, and two outs later, Scott Eyre faced pinch-hitter Geoff Blum. Eyre grabbed Blum's roller down the first-base line just before it went foul as it was kicking up chalk, and the Padres had runners at the corners. Eyre then struck out Mark Bellhorn to end the inning.

He exchanged a few words with home plate umpire Jerry Meals on the Blum play, and later admitted that Meals made the right call.

"I thought it was foul -- he made the right call," Eyre said. "I tip my hat to him, and I'll apologize to him tomorrow. You say what you say in the moment and you move on. I moved on to get the next guy out, and he moved on to call a good game."

Sean Marshall pitched a great game. He was trying to become the first Cubs rookie to go 3-0 since Frank Castillo did so in 1991. The lefty did not get a decision, giving up one run on three hits and three walks over six innings while striking out six.

"I feel great and very comfortable out there," Marshall said. "It's still a learning process for me and I learned a couple things today. I have to keep picking up things along the road and hopefully keep going."

Marshall had a bumpy first inning, throwing 22 pitches. He then shifted into cruise control and retired eight in a row before walking Mike Cameron for the second time in the game to open the Padres' fourth.

San Diego collected all of its hits off Marshall in the sixth. With one out, Young slapped an 0-1 pitch to left for the first hit. Cameron then reached on an infield single, beating Marshall and the throw to the bag by a half step on what he called an "in-between ball." Brian Giles singled for the third straight hit off the rookie lefty. Young scored and tied the game at 1.

"I knew I was pitching good in the first five innings but a no-hitter doesn't come into your thoughts," he said. "You keep making good pitches and keep putting zeros on the board to give us a good chance to win."

Ramirez's home run leading off the fourth was the first by a Cub in seven games. It also ended the string of scoreless innings at 28, the team's longest since a 36-inning stretch that lasted from April 27-May 1, 1992.

The Cubs had their running shoes on and swiped five bases in the game -- two each by Ronny Cedeno and Matt Murton. It's the first time they've stolen five since June 1, 2000, against Atlanta.

They came close to ending the scoreless-innings stretch in the first when Cedeno reached on an infield single with one out, stole second and advanced to third on a flyout by Todd Walker. But first baseman Bellhorn snared Jones' ball on the line and recovered in time to throw him out.

For the game, the Cubs were 0-for-13 with runners in scoring position. In their last eight games, they're 4-for-56 (.071).

"Marshall pitched great," Baker said. "We left a lot of guys out there and had a lot of chances. It was big with the runner on third [three times] and we didn't pick him up. We're just not getting a hit at the right time. When the games are close, whoever gets the hit, it's game time."

This story was not subject to the approval of Major League Baseball or its clubs.